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  1.  
    Just hit the airwaves. This is an antihisamine that may actually reverse some symptoms of AD. Have any of you heard of it?
    • CommentAuthorcarma
    • CommentTimeJul 21st 2008
     
    Joan has a link on her homepage to the study of dimebon
    • CommentAuthorSunshyne
    • CommentTimeJul 21st 2008
     
    Yes, it has just completed a small Phase II in Russia and the results looked good. They are now recruiting for Phase III in the U.S. There will be two trials. For one, the patient can NOT be on any prescription AD drugs. For the other, the patient MUST be on aricept.

    http://www.medivation.com/pipeline_alzheimer.html

    http://www.memorycenternj.com/index.php/uncategorized/what-is-the-bottom-line-of-the-dimebon-report
  2.  
    Dimebon was in the news tonight. I was in the kitchen and didn't hear all of it but did hear that it was expected to get FDA approved. Are we close to having a better drug to treat AD?
    • CommentAuthorGuitarGuy
    • CommentTimeNov 3rd 2008
     
    Anybody know anyone who is in the trial??

    Yes I did call and since my wife is on both, they recommend not stopping the meds.
    • CommentAuthorGuitarGuy
    • CommentTimeNov 3rd 2008
     
    Have there been other medications that have actually said that they could "REVERSE" AD symptoms?

    Does anyone here believe that dimebon can?

    I'm just asking for gut feelings and/or any research anyone has done?

    I had called them but since my wife is already on Aricept and Namenda they said she wasn't eligible and they recommend not stopping the meds.

    guy
    • CommentAuthorbrianna
    • CommentTimeApr 3rd 2009
     
    Thought I bring this up and see if anyone has enrolled in a Dimebon trial. I'm extremely interested in one if you can remain on Aricept.
  3.  
    I know it was discussed (and dismissed!!!!!) at the International Conference on Alzheimer's in Chicago last summer. Our Neurologist wa on a major panel - and she said it was nonsense...She further said the doctor that was promoting it was one of the owners of the pharmacedical company that was making the drug. oops!

    She said his presentation did not make one iota of sense to the panels and his studies were basically invalid.
    • CommentAuthorSunshyne
    • CommentTimeApr 4th 2009
     
    brianna,

    Go to:

    http://clinicaltrial.gov/ct2/search

    and enter:

    dimebon and alzheimer's

    then click on "search"

    There are several trials recruiting or getting ready to recruit that will allow the patient to be on aricept (donepezil).

    They don't have all the study locations listed yet for some of these trials. I've been told dimebon will be tested in at least two places in San Diego, and neither one is showing yet, so if you don't find a location near you, keep checking back.
    • CommentAuthorbrianna
    • CommentTimeApr 7th 2009
     
    I've found a trial going on in Winston-Salem and I think DH has a good chance of getting into this one. It seems to be the most promising drug so far from what I've read, so I'm very excited.