Press release re journal called "Cell" dated Sept 10, 2010:
FUNCTION FOUND FOR ALZHEIMER'S PROTEIN
In people with Alzheimer's, the brain becomes riddled with clumps of protein, forming what are known as amyloid plaques. Now, a report appearing in the September 17th print issue of Cell appears to have found a function for the amyloid precursor protein (APP for short) that yields the prime ingredient in those plaques.
It turns out that APP is an iron oxidase whose job it is to convert iron from an unsafe form to a safe one for transport or storage. When APP fails to function properly, as it does in Alzheimer's disease, iron levels inside neurons mount to toxic levels.
Yeah...it takes some re-reading, and thinking to grasp it all. I guess my hippie brother-in-law was not totally off base when his naturopathic doc did a heavy metals test on Jeff a few years back. Not that it helped.